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HomeProduct name listDELAPRIL HCL

DELAPRIL HCL

DELAPRIL HCL Structural

What is DELAPRIL HCL?

Description

Delapril is a new angiotensin-converting enzyme (ACE) inhibitor useful in the treatment of essential hypertension. Orally administered delapril is a prodrug which is de-esterified to its active diacid metabolite. In hypertensive patients delapril significantly decreased systolic blood pressure and ACE activity 24 hours after dosing without affecting endogeneous creatinine clearance.

Originator

Takeda (Japan)

The Uses of DELAPRIL HCL

Antihypertensive; enzyme inhibitor (angiotensinconverting).

The Uses of DELAPRIL HCL

Delapril Hydrochloride is an angiotensin-converting-enzyme inhibitor (ACE) used as an antihypertensive drug in some European and Asian countries, but not in America.

Definition

ChEBI: Delapril hydrochloride is a peptide.

brand name

Adecut

Properties of DELAPRIL HCL

Melting point: 166-170℃
alpha  D22 +18.5° (c = 1 in methanol)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO:174.0(Max Conc. mg/mL);355.82(Max Conc. mM)
form  Solid
color  White to off-white
CAS DataBase Reference 83435-67-0(CAS DataBase Reference)

Safety information for DELAPRIL HCL

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for DELAPRIL HCL

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