DELAPRIL HCL
- CAS NO.：83435-67-0
- Empirical Formula: C26H32N2O5.HCl
- Molecular Weight: 0
- MDL number: MFCD00884619
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is DELAPRIL HCL?
Description
Delapril is a new angiotensin-converting enzyme (ACE) inhibitor useful in the treatment of essential hypertension. Orally administered delapril is a prodrug which is de-esterified to its active diacid metabolite. In hypertensive patients delapril significantly decreased systolic blood pressure and ACE activity 24 hours after dosing without affecting endogeneous creatinine clearance.
Originator
Takeda (Japan)
The Uses of DELAPRIL HCL
Antihypertensive; enzyme inhibitor (angiotensinconverting).
The Uses of DELAPRIL HCL
Delapril Hydrochloride is an angiotensin-converting-enzyme inhibitor (ACE) used as an antihypertensive drug in some European and Asian countries, but not in America.
Definition
ChEBI: Delapril hydrochloride is a peptide.
brand name
Adecut
Properties of DELAPRIL HCL
| Melting point: | 166-170℃ |
| alpha | D22 +18.5° (c = 1 in methanol) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO:174.0(Max Conc. mg/mL);355.82(Max Conc. mM) |
| form | Solid |
| color | White to off-white |
| CAS DataBase Reference | 83435-67-0(CAS DataBase Reference) |
Safety information for DELAPRIL HCL
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DELAPRIL HCL
DELAPRIL HCL manufacturer
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