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HomeProduct name listMethoxypolyethylene glycols

Methoxypolyethylene glycols

Synonym(s):Methoxy poly(ethylene glycol);Methoxypolyethylene glycol;mPEG;Poly(ethylene glycol) methyl ether;Polyethylene glycol monomethyl ether

  • CAS NO.:9004-74-4
  • Empirical Formula: C5H12O3
  • Molecular Weight: 120.14698
  • MDL number: MFCD00084416
  • EINECS: 618-394-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:57
Methoxypolyethylene glycols Structural

What is Methoxypolyethylene glycols?

Description

m-PEG36-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Chemical properties

varies from viscous liquid to white flakes, depending

The Uses of Methoxypolyethylene glycols

enteric coating controlled release and enteric release coatings

The Uses of Methoxypolyethylene glycols

Methoxypolyethylene Glycol of with an average molecular mass of 350. Methoxypolyethylene Glycol (MPEG) is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.

The Uses of Methoxypolyethylene glycols

Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes. It has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.

What are the applications of Application

Methoxypolyethylene glycol 350 is a polyethylene glycol

Definition

ChEBI: A poly(ethylene glycol) terminated with a methyl group at one end.

brand name

Carbowax Sentry Methoxypolyethylene Glycol (Union Carbide).

General Description

It is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether. Etherification of the PEG chain ends can be undertaken in basic conditions by reacting it with alkyl halides. mPEG can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.

Properties of Methoxypolyethylene glycols

Melting point: 60-64 °C
Boiling point: >200°C/760mmHg
Density  1.094 g/mL at 25 °C
vapor density  >1 (vs air)
vapor pressure  0.05 mm Hg ( 20 °C)
refractive index  n20/D 1.459
Flash point: 268 °C
storage temp.  -20°C
solubility  H2O: 50 mg/mL at 25 °C, clear, colorless
form  semisolid
color  White to pale yellow
Specific Gravity 1.094
PH 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility  Slightly miscible with water.
λmax λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03
Stability: Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
EPA Substance Registry System Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy- (9004-74-4)

Safety information for Methoxypolyethylene glycols

Computed Descriptors for Methoxypolyethylene glycols

InChIKey XNWFRZJHXBZDAG-UHFFFAOYSA-N

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