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HomeProduct name listDBCO-SE

DBCO-SE

Synonym(s):DBCO-NHS ester;DBCO-SE

  • Molecular Weight: 0
  • MDL number: MFCD24386367
  • Update Date: 2023-04-23 13:52:06

What is DBCO-SE?

The Uses of DBCO-SE

Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.

Applications Include:

  • Protein-peptide conjugates
  • Antibody-enzyme or antibody-drug conjugates
  • Protein or peptide-oligonucleotide conjugates
  • Surface modification

Properties of DBCO-SE

Melting point: 149-157 (decomposition)
storage temp.  -20°C
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White to Off-White
Stability: Moisture Sensitive

Safety information for DBCO-SE

Computed Descriptors for DBCO-SE

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