Danofloxacin mesylate

Description

Danofloxacin is a fluoroquinolone antibiotic. In vitro, danofloxacin has activity against 68 field isolates of Mycoplasma species isolated from cattle, swine, and poultry with MICs ranging from 8 to 500 nM. It is protective in vivo against P. multocida, E. coli, and S. choleraesuis in mice with protective doses of 0.31, 0.40, and 2.42 mg/kg, respectively. Formulations containing danofloxacin are widely used to prevent infectious disease in livestock.

Chemical properties

Crystalline Solid

The Uses of Danofloxacin mesylate

Danofloxacin is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM

The Uses of Danofloxacin mesylate

Fluorinated quinolone antibacterial.

The Uses of Danofloxacin mesylate

Fluorinated quinolone antibacterial

Definition

ChEBI: Danofloxacin mesylate is a member of quinolines.

What are the applications of Application

Danofloxacin Mesylate is fluorinated quinolone antibacterial

Veterinary Drugs and Treatments

Danofloxacin mesylate injection is indicated for the treatment of Bovine Respiratory Disease (BRD) associated with Mannheimia (Pasturella) hemolytica and P. multocida in cattle (not dairy or veal). Because of the drug’s spectrum of activity, it may also be of benefit in the treatment of infections caused by Histophilus somni (Haemophilus somnus) or M. bovis, but the drug is not labeled (at the time of writing) for treating these pathogens. In other countries, danofloxacin may be labeled for use in swine and chickens (non-laying), but in the USA it is illegal to use the drug in an extralabel manner in food-producing species.
Danofloxacin may be of benefit in treating susceptible infections in adult horses, camelids and other non-food producing species.