D-SACCHARIC ACID 1 4-LACTONE
Synonym(s):D -Glucaric acid-1,4-lactone;D -Saccharolactone
- CAS NO.：61278-30-6
- Empirical Formula: C6H10O8
- Molecular Weight: 210.14
- MDL number: MFCD00149334
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is D-SACCHARIC ACID 1 4-LACTONE?
Chemical properties
White Solid
The Uses of D-SACCHARIC ACID 1 4-LACTONE
Anticancer agent
The Uses of D-SACCHARIC ACID 1 4-LACTONE
Anticancer agent.
The Uses of D-SACCHARIC ACID 1 4-LACTONE
D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.
What are the applications of Application
D-Saccharic acid 1,4-lactone monohydrate is an anticancer agent, used as a constituent of phosphate buffer to inhibit incidental β-glucuronidase activity.
General Description
D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).
Properties of D-SACCHARIC ACID 1 4-LACTONE
| Melting point: | 80-82°C |
| storage temp. | 2-8°C |
| solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| BRN | 85594 |
Safety information for D-SACCHARIC ACID 1 4-LACTONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for D-SACCHARIC ACID 1 4-LACTONE
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