D-SACCHARIC ACID 1 4-LACTONE
Synonym(s):D -Glucaric acid-1,4-lactone;D -Saccharolactone
- CAS NO.:61278-30-6
- Empirical Formula: C6H10O8
- Molecular Weight: 210.14
- MDL number: MFCD00149334
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is D-SACCHARIC ACID 1 4-LACTONE?
Chemical properties
White Solid
The Uses of D-SACCHARIC ACID 1 4-LACTONE
Anticancer agent
The Uses of D-SACCHARIC ACID 1 4-LACTONE
Anticancer agent.
The Uses of D-SACCHARIC ACID 1 4-LACTONE
D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.
What are the applications of Application
D-Saccharic acid 1,4-lactone monohydrate is an anticancer agent, used as a constituent of phosphate buffer to inhibit incidental β-glucuronidase activity.
General Description
D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).
Properties of D-SACCHARIC ACID 1 4-LACTONE
Melting point: | 80-82°C |
storage temp. | 2-8°C |
solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
BRN | 85594 |
Safety information for D-SACCHARIC ACID 1 4-LACTONE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for D-SACCHARIC ACID 1 4-LACTONE
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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