D-SACCHARIC ACID 1 4-LACTONE

Synonym(s):D-Glucaric acid-1,4-lactone;D-Saccharolactone

CAS NO.：61278-30-6
Empirical Formula: C6H10O8
Molecular Weight: 210.14
MDL number: MFCD00149334
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-31 13:32:20

What is D-SACCHARIC ACID 1 4-LACTONE?

Chemical properties

White Solid

The Uses of D-SACCHARIC ACID 1 4-LACTONE

Anticancer agent

The Uses of D-SACCHARIC ACID 1 4-LACTONE

Anticancer agent.

The Uses of D-SACCHARIC ACID 1 4-LACTONE

D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.

What are the applications of Application

D-Saccharic acid 1,4-lactone monohydrate is an anticancer agent, used as a constituent of phosphate buffer to inhibit incidental β-glucuronidase activity.

General Description

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).

Properties of D-SACCHARIC ACID 1 4-LACTONE

Melting point:	80-82°C
storage temp.	2-8°C
solubility	Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
BRN	85594

Safety information for D-SACCHARIC ACID 1 4-LACTONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.