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HomeProduct name listD-Mannosamine hydrochloride

D-Mannosamine hydrochloride

Synonym(s):D-Mannosamine hydrochloride;2-Amino-2-deoxy-D-mannose hydrochloride

  • CAS NO.:5505-63-5
  • Empirical Formula: C6H14ClNO5
  • Molecular Weight: 215.63
  • MDL number: MFCD00064557
  • EINECS: 226-847-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 11:59:05
D-Mannosamine hydrochloride  Structural

What is D-Mannosamine hydrochloride ?

Chemical properties

D-Mannosamine hydrochloride is White Crystalline Solid

The Uses of D-Mannosamine hydrochloride

D-Mannosamine hydrochloride is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery via M cells of Peyer's patches.

The Uses of D-Mannosamine hydrochloride

D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer's patches.

The Uses of D-Mannosamine hydrochloride

D-Mannosamine hydrochloride can be used for the synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. It has been used in a study to investigate the synthesis and high-throughput screening of N-acetyl-β-hexosaminidase inhibitor libraries targeting osteoarthritis.

Properties of D-Mannosamine hydrochloride

Melting point: 168 °C (dec.)(lit.)
storage temp.  2-8°C
solubility  H2O: 0.1 g/mL, clear, colorless
form  Powder
color  White to Off-white
Water Solubility  Soluble in water and methanol.
Sensitive  Hygroscopic
BRN  3914860
CAS DataBase Reference 5505-63-5(CAS DataBase Reference)
EPA Substance Registry System D-Mannose, 2-amino-2-deoxy-, hydrochloride (5505-63-5)

Safety information for D-Mannosamine hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P270:Do not eat, drink or smoke when using this product.
P271:Use only outdoors or in a well-ventilated area.
P272:Contaminated work clothing should not be allowed out of the workplace.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P310:Immediately call a POISON CENTER or doctor/physician.
P330:Rinse mouth.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P233:Store in a well-ventilated place. Keep container tightly closed.

Computed Descriptors for D-Mannosamine hydrochloride

InChIKey QKPLRMLTKYXDST-OHXGPSCHSA-N

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