D-GLUCOHEPTONO-1,4-LACTONE

CAS NO.：60046-25-5
Empirical Formula: C7H12O7
Molecular Weight: 208.17
MDL number: MFCD00005390
EINECS: 262-037-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is D-GLUCOHEPTONO-1,4-LACTONE?

Chemical properties

D-GLUCOHEPTONO-1,4-LACTONE is white fine crystalline powder

The Uses of D-GLUCOHEPTONO-1,4-LACTONE

D-GLUCOHEPTONO-1,4-LACTONE is used in the synthesis of Howiinol A and its analogs. D-GLUCOHEPTONO-1,4-LACTONE was one of the active antitumor constituents from the root and stem bark of Goniothamus howii (Annonaceae), and it was synthesized in 9 steps from α-D-glucoheptonic γ-lactone. Twenty-six analogs were also synthesized in searching for new antitumor compounds with high potency.

The Uses of D-GLUCOHEPTONO-1,4-LACTONE

It is used in the synthesis of Howiinol A and its analogs. Howiinol A was one of the active antitumor constituents from the root and stem bark of Goniothamus howii (Annonaceae), and it was synthesized in 9 steps from α-D-glucoheptonic γ-lactone. Twenty-six analogs were also synthesized in searching for new antitumor compounds with high potency.

Properties of D-GLUCOHEPTONO-1,4-LACTONE

Melting point:	152-155 °C(lit.)
Boiling point:	267.35°C (rough estimate)
Density	1.3807 (rough estimate)
refractive index	1.4455 (estimate)
storage temp.	Refrigerator, Under Inert Atmosphere
solubility	DMSO (Slightly), Water (Slightly)
pka	12.05±0.60(Predicted)
form	Solid
color	White to Pale Beige

Safety information for D-GLUCOHEPTONO-1,4-LACTONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.