D(-)-AMETHOPTERIN
Synonym(s):(−)-Amethopterin
- CAS NO.:51865-79-3
- Empirical Formula: C20H22N8O5
- Molecular Weight: 454.44
- MDL number: MFCD00006710
- EINECS: 257-482-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:35
What is D(-)-AMETHOPTERIN?
Chemical properties
Solid
The Uses of D(-)-AMETHOPTERIN
R-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
Properties of D(-)-AMETHOPTERIN
Melting point: | 195 °C |
Boiling point: | 561.26°C (rough estimate) |
Density | 1.4080 (rough estimate) |
refractive index | 1.6910 (estimate) |
storage temp. | -20°C |
solubility | Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly) |
pka | 3.47±0.10(Predicted) |
form | Solid |
color | Dark Yellow to Very Dark Yellow |
Stability: | Hygroscopic |
Safety information for D(-)-AMETHOPTERIN
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H341:Germ cell mutagenicity |
Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for D(-)-AMETHOPTERIN
New Products
Tubulysin E (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin I 2,2-diethoxyethanethioamide 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 4,4-DIFLUOROPIPERIDINE 4-(Benzyloxy)-3-bromophenylacetic Acid 2,2-Difluoropropanol Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH Fuel shell Lubiprostone Magnesium Trisilicate Latanoprostene Bunod Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-
2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE
Methotrexate EP Impurity G
N-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACID
Aminopterin
Methotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride)
(+)-Amethopterin-methyl-d3, 4-Amino-10-methylpteroylglutamic-methyl-d3 Acid
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