D(-)-AMETHOPTERIN
Synonym(s):(−)-Amethopterin
- CAS NO.：51865-79-3
- Empirical Formula: C20H22N8O5
- Molecular Weight: 454.44
- MDL number: MFCD00006710
- EINECS: 257-482-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:35
What is D(-)-AMETHOPTERIN?
Chemical properties
Solid
The Uses of D(-)-AMETHOPTERIN
R-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
Properties of D(-)-AMETHOPTERIN
| Melting point: | 195 °C |
| Boiling point: | 561.26°C (rough estimate) |
| Density | 1.4080 (rough estimate) |
| refractive index | 1.6910 (estimate) |
| storage temp. | -20°C |
| solubility | Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly） |
| pka | 3.47±0.10(Predicted) |
| form | Solid |
| color | Dark Yellow to Very Dark Yellow |
| Stability: | Hygroscopic |
Safety information for D(-)-AMETHOPTERIN
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for D(-)-AMETHOPTERIN
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