D-2-Phenylglycine
Synonym(s):(R)-(−)-2-Phenylglycine;D -2-Phenylglycine;R-(−)-α-Aminophenylacetic acid
- CAS NO.：875-74-1
- Empirical Formula: C8H9NO2
- Molecular Weight: 151.16
- MDL number: MFCD00008061
- EINECS: 212-876-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is D-2-Phenylglycine?
Description
d-Phenylglycine is widely used in large quantity as the side chain that makes ampicillin and cephalexin orally acceptable.
Chemical properties
White crystalline powder
The Uses of D-2-Phenylglycine
D-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA r eceptors.
The Uses of D-2-Phenylglycine
D-(-)-2-Phenylglycine (Cefalexin EP Impurity A) is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Definition
ChEBI: The R stereoisomer of alpha-phenylglycine.
Flammability and Explosibility
Non flammable
Synthesis
Industrially, dphenylglycine
has been produced by a conventional
resolution method or by kinetic resolution
with acylase. Another enzymatic procedure has
been developed by Yamada et al. ,
as shown below.
Properties of D-2-Phenylglycine
| Melting point: | 302 °C (dec.)(lit.) |
| Boiling point: | 273.17°C (rough estimate) |
| alpha | -156 º (c=1,1N HCl) |
| Density | 1.2 g/cm3 (20℃) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | -158 ° (C=1, 1mol/L HCl) |
| Flash point: | 150 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Aqueous Acid (Sparingly), Water (Slightly, Heated) |
| form | Crystalline Powder |
| pka | 1.94±0.10(Predicted) |
| color | White |
| optical activity | [α]20/D 155°, c = 1 in 1 M HCl |
| Water Solubility | 0.3g/100mL |
| Merck | 14,7291 |
| BRN | 2208676 |
| CAS DataBase Reference | 875-74-1(CAS DataBase Reference) |
| NIST Chemistry Reference | d a-Phenylglycine(875-74-1) |
| EPA Substance Registry System | Benzeneacetic acid, .alpha.-amino-, (.alpha.R)- (875-74-1) |
Safety information for D-2-Phenylglycine
Computed Descriptors for D-2-Phenylglycine
D-2-Phenylglycine manufacturer
JSK Chemicals
2Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: D-(-)-alpha-Phenylglycine, 98% 99%
Ebenezer Industries
Phone:+91-7600807590
Whatsapp: +91- 7600807590
product: D-alpha-Phenylglycine 875-74-1 98%
Atul Bioscience Ltd
1Y
Phone:+91-9316723499
Whatsapp: +91 9316723499
product: 875-74-1 D-alpha-Phenylglycine 99%
Anand Agencies
Maharashtra
Phone:91-9075014125
Whatsapp: 91-9075014125
product: D-alpha-Phenylglycine
Chemfield Inc
Maharashtra
Phone:91-9820165799
Whatsapp: 91-9820165799
product: D-alpha-Phenylglycine
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: D-alpha-Phenylglycine
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![(6R-trans)-7-[(2,2-diMethyl-1-oxopropyl)aMino]-3-Methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-](https://img.chemicalbook.in/CAS/GIF/146794-70-9.gif)
You may like
-
875-74-1 Cefaclor EP Impurity A 99%View Details
875-74-1 -
D-alpha-Phenylglycine 99%View Details -
D(-)-alpha-Phenylglycine 99% (HPLC) CAS 875-74-1View Details
875-74-1 -
D-2-Phenylglycine 98% CAS 875-74-1View Details
875-74-1 -
D-Phenylglycine, 99% CAS 875-74-1View Details
875-74-1 -
D-2-Phenylglycine CAS 875-74-1View Details
875-74-1 -
D-(-)-alpha-Phenylglycine CAS 875-74-1View Details
875-74-1 -
D−(−)-α-Phenylglycine CAS 875-74-1View Details
875-74-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.