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HomeProduct name listCytidine 5'-triphosphate disodium salt

Cytidine 5'-triphosphate disodium salt

Synonym(s):CTP

  • CAS NO.:36051-68-0
  • Empirical Formula: C9H17N3NaO14P3
  • Molecular Weight: 507.15
  • MDL number: MFCD00078193
  • EINECS: 252-849-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-09-11 18:44:42
Cytidine 5'-triphosphate disodium salt Structural

What is Cytidine 5'-triphosphate disodium salt?

Chemical properties

White powder

The Uses of Cytidine 5'-triphosphate disodium salt

Cytidine 5'-triphosphate disodium salt is a pyrimidine nucleoside triphosphate salt that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.[Cayman Chemical]

The Uses of Cytidine 5'-triphosphate disodium salt

Cytidine-5'-triphosphate disodium salt is a cation-permeable ligand gated ion channel (P2X purinergic receptor) agonist. It is also used as an organic intermediate, pharmaceutical intermediate, food additive and flavoring agent.

What are the applications of Application

Cytidine 5′-triphosphate disodium salt is a P2X purinergic receptor agonist

General Description

Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.

Biochem/physiol Actions

Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.

Properties of Cytidine 5'-triphosphate disodium salt

Flash point: 113 °C
storage temp.  -20°C
solubility  H2O: 50 mg/mL, clear, colorless
form  Powder
color  White
Water Solubility  Soluble in water. Insoluble in ethanol, chloroform and ether.
CAS DataBase Reference 36051-68-0(CAS DataBase Reference)

Safety information for Cytidine 5'-triphosphate disodium salt

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Cytidine 5'-triphosphate disodium salt

InChIKey LGADHEWLYMMGHW-RFFBCSJBNA-N
SMILES O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,19,r|

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