Cytidine 5'-triphosphate disodium salt
Synonym(s):CTP
- CAS NO.:36051-68-0
- Empirical Formula: C9H17N3NaO14P3
- Molecular Weight: 507.15
- MDL number: MFCD00078193
- EINECS: 252-849-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-11 18:44:42
What is Cytidine 5'-triphosphate disodium salt?
Chemical properties
White powder
The Uses of Cytidine 5'-triphosphate disodium salt
Cytidine 5'-triphosphate disodium salt is a pyrimidine nucleoside triphosphate salt that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.[Cayman Chemical]
The Uses of Cytidine 5'-triphosphate disodium salt
Cytidine-5'-triphosphate disodium salt is a cation-permeable ligand gated ion channel (P2X purinergic receptor) agonist. It is also used as an organic intermediate, pharmaceutical intermediate, food additive and flavoring agent.
What are the applications of Application
Cytidine 5′-triphosphate disodium salt is a P2X purinergic receptor agonist
General Description
Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.
Biochem/physiol Actions
Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.
Properties of Cytidine 5'-triphosphate disodium salt
Flash point: | 113 °C |
storage temp. | -20°C |
solubility | H2O: 50 mg/mL, clear, colorless |
form | Powder |
color | White |
Water Solubility | Soluble in water. Insoluble in ethanol, chloroform and ether. |
CAS DataBase Reference | 36051-68-0(CAS DataBase Reference) |
Safety information for Cytidine 5'-triphosphate disodium salt
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Cytidine 5'-triphosphate disodium salt
InChIKey | LGADHEWLYMMGHW-RFFBCSJBNA-N |
SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,19,r| |
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