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HomeProduct name listCyclopropylboronic acid pinacol ester

Cyclopropylboronic acid pinacol ester

Synonym(s):2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Cyclopropylboronic acid pinacol ester Structural

What is Cyclopropylboronic acid pinacol ester?

Chemical properties

Colorless liquid

The Uses of Cyclopropylboronic acid pinacol ester

Cyclopropylboronic acid pinacol ester can be used:

  • As a cyclopropylating reagent in the study of thiophenol S-cyclopropylation, catalyzed by copper(II) acetate.
  • In one of the key synthetic steps for the preparation of 5-lipoxygenase activating protein (FLAP) inhibitor.

The Uses of Cyclopropylboronic acid pinacol ester

suzuki reaction

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 4815, 1989 DOI: 10.1016/S0040-4039(01)80516-5

Properties of Cyclopropylboronic acid pinacol ester

Boiling point: 146 °C
Density  0.922 g/mL at 25 °C
refractive index  n20/D 1.433
Flash point: 104 °F
storage temp.  Inert atmosphere,Room Temperature
form  liquid
color  colorless
Sensitive  Moisture Sensitive
CAS DataBase Reference 126689-01-8(CAS DataBase Reference)

Safety information for Cyclopropylboronic acid pinacol ester

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
GHS Hazard Statements H226:Flammable liquids
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

Computed Descriptors for Cyclopropylboronic acid pinacol ester

InChIKey XGBMQBPLWXTEPM-UHFFFAOYSA-N

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