CYCLOPROPANECARBOTHIOAMIDE
- CAS NO.:20295-34-5
- Empirical Formula: C4H7NS
- Molecular Weight: 101.17
- MDL number: MFCD09469287
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-10 09:26:26
What is CYCLOPROPANECARBOTHIOAMIDE?
Description
Cyclopropanecarbothioamide is used for purification of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas during the simple-step reaction. It is also a useful chemical during the proteomics study. Recent study has also used it for synthesis of a novel heterocyclic compound, CE-125, which can improve working memory in the radial arm maze and modulate the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.
The Uses of CYCLOPROPANECARBOTHIOAMIDE
Cyclopropanecarbothioamide is used for purification in single-step preparation of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas.
References
https://www.alfa.com/en/catalog/H32315/
Hussein, A. M., et al. "A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat." Behavioural Brain Research 332(2017):308-315.
Properties of CYCLOPROPANECARBOTHIOAMIDE
Melting point: | 111-113℃ |
Boiling point: | 176.9±23.0 °C(Predicted) |
Density | 1.272±0.06 g/cm3(Predicted) |
pka | 13.19±0.20(Predicted) |
CAS DataBase Reference | 20295-34-5 |
Safety information for CYCLOPROPANECARBOTHIOAMIDE
Signal word | Warning |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P321:Specific treatment (see … on this label). P405:Store locked up. |
Computed Descriptors for CYCLOPROPANECARBOTHIOAMIDE
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Rimegepant Impurity 3 Fosfomycin EP impurity D Ivermectin EP Impurity B Tubulysin C Tubulysin G Tubulysin F (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin M (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 4,7-Dibromobenzo[c][1,2,5]thiadiazole-5,6-diamine 3,3,6,6-Tetramethylcyclohexane-1,2-dione Diethyl 2,5-di(furan-2-yl)terephthalate Methyl 4-amino-3-(piperidin-1-yl)benzoate 2-Ethoxy-4-nitrobenzoic acid 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione (4R,12aR)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1`,2`;4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid 6-bromopyridazin-3-amineRelated products of tetrahydrofuran
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