CYCLOPROPANECARBOTHIOAMIDE

CAS NO.：20295-34-5
Empirical Formula: C4H7NS
Molecular Weight: 101.17
MDL number: MFCD09469287
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-10 09:26:26

What is CYCLOPROPANECARBOTHIOAMIDE?

Description

Cyclopropanecarbothioamide is used for purification of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas during the simple-step reaction. It is also a useful chemical during the proteomics study. Recent study has also used it for synthesis of a novel heterocyclic compound, CE-125, which can improve working memory in the radial arm maze and modulate the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.

The Uses of CYCLOPROPANECARBOTHIOAMIDE

Cyclopropanecarbothioamide is used for purification in single-step preparation of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas.

References

https://www.alfa.com/en/catalog/H32315/
Hussein, A. M., et al. "A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat." Behavioural Brain Research 332(2017):308-315.

Properties of CYCLOPROPANECARBOTHIOAMIDE

Melting point:	111-113℃
Boiling point:	176.9±23.0 °C(Predicted)
Density	1.272±0.06 g/cm3(Predicted)
pka	13.19±0.20(Predicted)
CAS DataBase Reference	20295-34-5

Safety information for CYCLOPROPANECARBOTHIOAMIDE

Signal word	Warning
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P321:Specific treatment (see … on this label). P405:Store locked up.