Crotonyl alcohol

Synonym(s):2-Buten-1-ol

CAS NO.：6117-91-5
Empirical Formula: C4H8O
Molecular Weight: 72.11
MDL number: MFCD00002923
EINECS: 228-086-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-09-25 09:23:02

What is Crotonyl alcohol ?

Chemical properties

Clear light yellow liquid

The Uses of Crotonyl alcohol

Chemical intermediate, source of monomers, herbicide, and soil fumigant.

The Uses of Crotonyl alcohol

Crotyl alcohol can be used as a starting material in the synthesis of antitumor agents such as 14-azacamptothecin and 10, 11-methylenedioxy-14-azacamptothecin. It can also be used as a precursor in the total synthesis of discodermolide.

Definition

ChEBI: A primary alcohol in which the hydroxy function is bonded to a CH3CH2CHCH21 (crotyl) group.

Hazard

Toxic by ingestion, strong eye and skin irritant. Moderate fire risk.

Safety Profile

Moderately toxic by ingestion and skin contact. Mutation data reported. Dangerous fire hazard when exposed to heat or flame; can react with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and fumes. See also ALCOHOLS.

Properties of Crotonyl alcohol

Melting point:	-91.3°C (estimate)
Boiling point:	121-122 °C(lit.)
Density	0.845 g/mL at 25 °C(lit.)
refractive index	n20/D 1.427(lit.)
Flash point:	37 °C
storage temp.	Flammables area
solubility	Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
pka	14.70±0.10(Predicted)
form	clear liquid
color	Colorless to Almost colorless
Water Solubility	Miscible with water.
Merck	14,2601
BRN	1719374
CAS DataBase Reference	6117-91-5(CAS DataBase Reference)
NIST Chemistry Reference	2-Buten-1-ol(6117-91-5)
EPA Substance Registry System	2-Buten-1-ol (6117-91-5)

Safety information for Crotonyl alcohol

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection.