CRF (HUMAN, RAT)

Synonym(s):Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem;CRF;CRH

CAS NO.：86784-80-7
Empirical Formula: C208H344N60O63S2
Molecular Weight: 4757.45
MDL number: MFCD00213806
Update Date: 2023-06-30 15:45:59

What is CRF (HUMAN, RAT)?

The Uses of CRF (HUMAN, RAT)

Treatment of symptoms associated with peritumoral edema in brain tumor patients.

The Uses of CRF (HUMAN, RAT)

Corticotropin Releasing Factor human, rat has been used:

as a component in Dulbecco′s modified eagle medium (DMEM) for incubating lung explants
as a component in serum-free complete medium for isolation and culturing of fetal distal lung epithelial cells
in the synthesis of the corticotropin-releasing factor(CRF)-TAMRA?1?mixture
in chronic intracerebroventicular administration, to study its effect on hypoxia in hippocampus

brand name

Xerecept (Hollister-Stier) [Note—The source of the product (human, porcine, etc.) must be indicated in the labeling.].

General Description

Corticotropin-releasing factor is a 41-amino-acid polypeptide. It is expressed in neurons, hypothalamus?and amygdala.

Biochem/physiol Actions

CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.

storage

Store at -20°C

Properties of CRF (HUMAN, RAT)

storage temp.	−20°C
solubility	H2O : 16.66 mg/mL (3.50 mM; Need ultrasonic and warming)
form	White to off-white lyophilized solid
Water Solubility	Soluble to 1.10 mg/ml in water

Safety information for CRF (HUMAN, RAT)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.