CP-456773 sodium
Synonym(s):CRID3;Cytokine release inhibitory drug 3;MCC950;N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt
- CAS NO.:256373-96-3
- Empirical Formula: C20H23N2NaO5S
- Molecular Weight: 426.46179
- MDL number: MFCD30478884
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-15 19:19:13
What is CP-456773 sodium?
The Uses of CP-456773 sodium
CP-456773 sodium salt has been used :
- In in vivo experiments to study the neuroprotective action of ketogenic diet.
- To study the effect of inhibition of NLRP3 (nod-like receptor protein 3) inflammasome activity on tumor progression in mouse models.
- To study the cholesterol crystal-mediated IL-1b (interleukin-1b) response in placental explants.
Biochem/physiol Actions
CP-456773 is known to inhibit the release of other proinflammatory cytokines such as IL-1α and IL-18. It is also referred to as MCC950.
storage
+4°C
Properties of CP-456773 sodium
storage temp. | room temp |
solubility | Soluble in DMSO:50.0(Max Conc. mg/mL);117.24(Max Conc. mM) Water:30.0(Max Conc. mg/mL);70.35(Max Conc. mM) |
form | powder |
color | white to beige |
Safety information for CP-456773 sodium
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for CP-456773 sodium
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile Diclofenac Potassium Ornidazole IP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Aceclofenac IP/BP/EP Nimesulide BP SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION SODIUM METHYL PARABEN Methylcobalamin (vitamin B12) SODIUM VALPROATE Racecadotril XANTHAN GUMRelated products of tetrahydrofuran
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SRT1720
MG-132
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