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HomeProduct name listCONIFERYL ALCOHOL

CONIFERYL ALCOHOL

Synonym(s):3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-ol;4-Hydroxy-3-methoxycinnamyl alcohol

  • CAS NO.:458-35-5
  • Empirical Formula: C10H12O3
  • Molecular Weight: 180.2
  • MDL number: MFCD00002922
  • EINECS: 207-277-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
CONIFERYL ALCOHOL Structural

What is CONIFERYL ALCOHOL?

Chemical properties

beige crystalline powder

Physical properties

White (colorless) crystals. M.P. 74°C. Very slightly soluble in water, soluble in alcohol and oils.

The Uses of CONIFERYL ALCOHOL

Coniferyl alcohol was used as a fungal growth inhibitor.

Definition

ChEBI: A phenylpropanoid that is one of the main monolignols, produced by the reduction of the carboxy functional group in cinnamic acid and the addition of a hydroxy and a methoxy substituent to the aromatic ring.

What are the applications of Application

CONIFERYL ALCOHOL can polymerize with weak mineral acids and certain organic acids, turning into an amorphous, odorless gum. This chemical could find extensive use as a fixative and blender in various types of floral, balsamic and Oriental fragrances. However, it is not generally available in the state of chemical or olfactory purity desirable to the perfumer.

General Description

Coniferyl alcohol is one of the preferred substrate of the eucalpytus globus enzyme.

Purification Methods

It is soluble in EtOH and insoluble in H2O. It can, however, be recrystallised from EtOH and distilled in a vacuum. It polymerises in dilute acid. The benzoyl derivative has m 95-96o (from pet ether), and the tosylate has m 66o. [Derivatives: Freudenberg & Achtzehn Chem Ber 88 10 1955, UV: Herzog & Hillmer Chem Ber 64 1288 1931, Beilstein 6 II 1093.]

Properties of CONIFERYL ALCOHOL

Melting point: 75-80 °C(lit.)
Boiling point: 163-165 °C3 mm Hg(lit.)
Density  1.1272 (rough estimate)
RTECS  SL5367000
refractive index  1.5080 (estimate)
Flash point: 163-165°C/3mm
storage temp.  -20°C
solubility  alcohol: moderately soluble(lit.)
pka 9.99±0.35(Predicted)
form  Solid
color  Pale Yellow to Light Yellow
Sensitive  Light Sensitive
Merck  14,2504
BRN  2048961
Stability: Light Sensitive
CAS DataBase Reference 458-35-5(CAS DataBase Reference)
EPA Substance Registry System Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy- (458-35-5)

Safety information for CONIFERYL ALCOHOL

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for CONIFERYL ALCOHOL

InChIKey JMFRWRFFLBVWSI-UHFFFAOYSA-N

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