CONIFERYL ALCOHOL

Synonym(s):3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-ol;4-Hydroxy-3-methoxycinnamyl alcohol

CAS NO.：458-35-5
Empirical Formula: C10H12O3
Molecular Weight: 180.2
MDL number: MFCD00002922
EINECS: 207-277-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:08:52

What is CONIFERYL ALCOHOL?

Chemical properties

beige crystalline powder

Physical properties

White (colorless) crystals. M.P. 74°C. Very slightly soluble in water, soluble in alcohol and oils.

The Uses of CONIFERYL ALCOHOL

Coniferyl alcohol was used as a fungal growth inhibitor.

Definition

ChEBI: A phenylpropanoid that is one of the main monolignols, produced by the reduction of the carboxy functional group in cinnamic acid and the addition of a hydroxy and a methoxy substituent to the aromatic ring.

What are the applications of Application

CONIFERYL ALCOHOL can polymerize with weak mineral acids and certain organic acids, turning into an amorphous, odorless gum. This chemical could find extensive use as a fixative and blender in various types of floral, balsamic and Oriental fragrances. However, it is not generally available in the state of chemical or olfactory purity desirable to the perfumer.

General Description

Coniferyl alcohol is one of the preferred substrate of the eucalpytus globus enzyme.

Purification Methods

It is soluble in EtOH and insoluble in H2O. It can, however, be recrystallised from EtOH and distilled in a vacuum. It polymerises in dilute acid. The benzoyl derivative has m 95-96o (from pet ether), and the tosylate has m 66o. [Derivatives: Freudenberg & Achtzehn Chem Ber 88 10 1955, UV: Herzog & Hillmer Chem Ber 64 1288 1931, Beilstein 6 II 1093.]

Properties of CONIFERYL ALCOHOL

Melting point:	75-80 °C(lit.)
Boiling point:	163-165 °C3 mm Hg(lit.)
Density	1.1272 (rough estimate)
RTECS	SL5367000
refractive index	1.5080 (estimate)
Flash point:	163-165°C/3mm
storage temp.	-20°C
solubility	alcohol: moderately soluble(lit.)
pka	9.99±0.35(Predicted)
form	Solid
color	Pale Yellow to Light Yellow
Sensitive	Light Sensitive
Merck	14,2504
BRN	2048961
Stability:	Light Sensitive
CAS DataBase Reference	458-35-5(CAS DataBase Reference)
EPA Substance Registry System	Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy- (458-35-5)

Safety information for CONIFERYL ALCOHOL

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.