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HomeProduct name listCOELENTERAZINE HCP

COELENTERAZINE HCP

Synonym(s):CLZN-hcp

COELENTERAZINE HCP Structural

What is COELENTERAZINE HCP?

The Uses of COELENTERAZINE HCP

Coelenterazine hcp has been used:

  • as a component of coelenterazine reagent in the reporter assay
  • in the purification of Renilla luciferase-labeled Annexin V
  • in evaluating the activity of aequorin in Escherichia coli

General Description

Coelenterazine hcp is a semisynthetic analog of coelenterazine.

Biochem/physiol Actions

Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine.

Properties of COELENTERAZINE HCP

Melting point: >200℃
storage temp.  -20°C
solubility  Soluble in ethanol, methanol
form  solid
color  Yellow
λmax 433nm
Biological Applications Calcium indicator; assaying luminescent enzyme; measuring luciferase activity; as a substrate for luciferase; screening HIV-1 protease inhibitors; bioluminescence resonance energy transfer (BRET) detection system

Safety information for COELENTERAZINE HCP

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for COELENTERAZINE HCP

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