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HomeProduct name listCOCAINE HYDROCHLORIDE

COCAINE HYDROCHLORIDE

  • CAS NO.:53-21-4
  • Empirical Formula: C17H22ClNO4
  • Molecular Weight: 339.81
  • MDL number: MFCD00058119
  • EINECS: 200-167-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 09:02:51
COCAINE HYDROCHLORIDE Structural

What is COCAINE HYDROCHLORIDE?

Description

Cocaine (hydrochloride) (Item No. 22165) is an analytical reference standard categorized as a tropane. Cocaine has a high potential for abuse and has been found in samples seized by law enforcement. Cocaine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

Chemical properties

White Solid

The Uses of COCAINE HYDROCHLORIDE

Inhibits the dopamine, norepinephrine, and serotonin transporters. Unlike amphetamines, it has no effect on catecholamine release. Controlled substance. Anesthetic (local)

Definition

ChEBI: The hydrochloride salt of cocaine. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is drug of abuse.

Biological Activity

Competitive inhibitor of monoamine neurotransmitter transporters. Inhibits dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters with K i values are 267, 392 and 872 nM respectively. Psychostimulant.

Properties of COCAINE HYDROCHLORIDE

Melting point: 200-2020C
alpha  D -72° (c = 2 in aq soln pH 4.5)
storage temp.  2-8°C
solubility  Very soluble in water, freely soluble in alcohol, slightly soluble in methylene chloride.
form  Powder
Water Solubility  Soluble to 100 mM in water
CAS DataBase Reference 53-21-4
EPA Substance Registry System 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride (1:1), (1R,2R,3S,5S)- (53-21-4)

Safety information for COCAINE HYDROCHLORIDE

Computed Descriptors for COCAINE HYDROCHLORIDE

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