CLOXAZOLAM
- CAS NO.:24166-13-0
- Empirical Formula: C17H14Cl2N2O2
- Molecular Weight: 349.21
- MDL number: MFCD00868152
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:36
What is CLOXAZOLAM?
Originator
Sepazon,Sankyo,Japan,1974
The Uses of CLOXAZOLAM
CLOXAZOLAM is a benzodiazepine derivative with anxiolytic, hypnotic and antihypertensive properties used as an anti-anxiety drug. It is metabolized into the active metabolite Delorezepam (D230675). Controlled Subs tance.
Definition
ChEBI: Cloxazolam is an oxazolobenzodiazepine and a hemiaminal ether.
Manufacturing Process
As described in US Patent 3,772,371: To a solution of 5.8 g of 5-chloro-2-
bromoacetylamino-o-chlorobenzophenone in 120 ml of ethanol were added
0.95 g of ethanolamine and 1.3 g of sodium acetate. The resulting mixture
was heated under reflux for 16 hours.
After completion of the reaction, the solvent was distilled off and the residue
was extracted with dichloromethane. The extract was washed with water,
dried over anhydrous sodium sulfate and the solvent was distilled off to give
3.25 g of the desired product melting at 202° to 204°C with decomposition.
Therapeutic Function
Tranquilizer
Properties of CLOXAZOLAM
Melting point: | 202-204° (dec) |
Boiling point: | 172°C (rough estimate) |
Density | 1.4125 (rough estimate) |
refractive index | 1.6100 (estimate) |
pka | 12.70±0.40(Predicted) |
CAS DataBase Reference | 24166-13-0 |
Safety information for CLOXAZOLAM
Computed Descriptors for CLOXAZOLAM
Abamectin manufacturer
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
88491-46-7 98%View Details
88491-46-7 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4