Clorsulon
Synonym(s):4-Amino-6-(trichlorovinyl)-1,3-benzenedisulfonamide
- CAS NO.:60200-06-8
- Empirical Formula: C8H8Cl3N3O4S2
- Molecular Weight: 380.66
- MDL number: MFCD00072006
- EINECS: 262-100-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is Clorsulon?
Description
Clorsulon is a sulfonamide antiparasitic agent. It induces swelling and blebbing and reduces motility of F. hepatica mature flukes when used at a concentration of 10 μg/ml. In vivo, clorsulon (3.5-15 mg/kg) reduces the number of flukes in a goat model of F. hepatica infection. It completely eradicates naturally acquired F. hepatica adult flukes in sheep and cattle when administered at a dose of 7 mg/kg. Formulations containing clorsulon have been used in the treatment of liver flukes in sheep and cattle.
Chemical properties
Crystalline Solid
The Uses of Clorsulon
analgesic, antiinflammatory
The Uses of Clorsulon
A benzenedisulfonamide derivative with fasciolicidal activity. Anthelmintic (Trematodes).
The Uses of Clorsulon
A benzenedisulfonamide derivative with fasciolicidal activity. Anthelmintic (Trematodes)
Definition
ChEBI: 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide is a sulfonamide and a member of benzenes.
What are the applications of Application
Clorsulon is A benzenedisulfonamide derivative with fasciolicidal activity
brand name
Curatrem [Veterinary] (Merial).
Veterinary Drugs and Treatments
Clorsulon is approved for use in the treatment of immature and adult forms of Fasciola hepatica (Liver fluke) in cattle. It is not effective against immature flukes less than 8 weeks old. It also has activity against Fasciola gigantica. Although not approved, the drug has been used in practice in various other species (e.g., sheep, llamas). It has activity against F. magna in sheep, but is not completely effective in eradicating the organism after a single dose, thus severely limiting its clinical usefulness against this parasite. Clorsulon is also not effective against the rumen fluke (Paramphistomum).
Properties of Clorsulon
Melting point: | 194-203°C |
Boiling point: | 651.7±65.0 °C(Predicted) |
Density | 1.800±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | neat |
pka | 9.16±0.60(Predicted) |
form | Solid |
color | White |
CAS DataBase Reference | 60200-06-8(CAS DataBase Reference) |
Safety information for Clorsulon
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Clorsulon
Clorsulon manufacturer
Manasvi Life Sciences
Ralington Pharma
Rakshit Group of Companies (Rakshit Drugs Pvt Ltd)
Noven Lifesciences Pvt Limited
Nulli Secondus Impex Pvt Ltd
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
60200-02-8 Clorsulon USPView Details
60200-02-8 -
CLORSULON 99%View Details
-
Clorsulon 98%View Details
60200-06-8 -
60200-06-8 99%View Details
60200-06-8 -
Clorsulon 99%View Details
60200-06-8 -
Clorsulon 60200-06-8 98%View Details
60200-06-8 -
Clorsulon Usp 99%View Details
-
Clorsulon CAS 60200-06-8View Details
60200-06-8