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HomeProduct name listCLOCORTOLONE PIVALATE

CLOCORTOLONE PIVALATE

  • CAS NO.:34097-16-0
  • Empirical Formula: C27H36ClFO5
  • Molecular Weight: 495.02
  • MDL number: MFCD00867450
  • EINECS: 251-826-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-23 13:36:13
CLOCORTOLONE PIVALATE Structural

What is CLOCORTOLONE PIVALATE?

The Uses of CLOCORTOLONE PIVALATE

Clocortolone Pivalate is a corticosteroid used in the treatment of atopic dermatitis.

Definition

ChEBI: The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders.

brand name

Cloderm (Healthpoint).

General Description

Clocortolone pivalate, 9-chloro-21-(2,2-dimethyl-1-oxopropoxy)-6α-fluoro-11β-hydroxy-16α-methylpregna-1,4-diene-3,20-dione (Cloderm),along with desoximetasone, lacks the C17α oxygen functionalitythat is present in other GCs but still retains goodGC activity.

Properties of CLOCORTOLONE PIVALATE

Melting point: 231-233°C
Boiling point: 598.0±50.0 °C(Predicted)
Density  1.24±0.1 g/cm3(Predicted)
storage temp.  Refrigerator, under inert atmosphere
solubility  Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form  Solid
pka 13.04±0.70(Predicted)
color  White

Safety information for CLOCORTOLONE PIVALATE

Computed Descriptors for CLOCORTOLONE PIVALATE

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