CITRATE SYNTHASE
Synonym(s):Citrate condensing enzyme;Citrate oxaloacetate lyase (CoA-acetylating)
- CAS NO.:9027-96-7
- Empirical Formula: C6H5O7-3
- Molecular Weight: 189.0997
- MDL number: MFCD00130808
- EINECS: 232-821-7
- Update Date: 2023-04-23 13:52:06
What is CITRATE SYNTHASE?
The Uses of CITRATE SYNTHASE
Citrate Synthase from porcine heart has been used:
- to inject newt egg for determining its importance in egg activation at fertilization
- in the preparation of reaction mix to determine pyruvate carboxylase enzyme activity
- to examine whether it can induce a [Ca2+]?increase and egg activation in unfertilized eggs
Definition
An enzyme that catalyzes the condensation of oxaloacetic acid and acetyl-CoA to yield citric acid and coenzyme A.
Biochem/physiol Actions
Citrate synthase catalyses the conversion of citrate to acetyl-CoA in the presence of coenzyme-A with the release of H2O and oxaloacetate. The enzyme has a molecular weight of 85 kDa and a pI of 6.1-6.6. It is inhibited by fluoroacetyl-CoA, palmitoyl-CoA, and citroyl-CoA. It is also inhibited when it is acetylated by acetic anhydride or iodinated by iodine.
Properties of CITRATE SYNTHASE
storage temp. | 2-8°C |
solubility | H2O: soluble1.0mg/mL, clear |
form | ammonium sulfate suspension |
Safety information for CITRATE SYNTHASE
Computed Descriptors for CITRATE SYNTHASE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
Cupric acetylacetonate
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
Benzyl isocyanide
Ethyl isocyanoacetate
Tris(2,4-pentanedionato)chroMiuM(III)
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