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HomeProduct name listCITRATE SYNTHASE

CITRATE SYNTHASE

Synonym(s):Citrate condensing enzyme;Citrate oxaloacetate lyase (CoA-acetylating)

  • CAS NO.:9027-96-7
  • Empirical Formula: C6H5O7-3
  • Molecular Weight: 189.0997
  • MDL number: MFCD00130808
  • EINECS: 232-821-7
  • Update Date: 2023-04-23 13:52:06
CITRATE SYNTHASE Structural

What is CITRATE SYNTHASE?

The Uses of CITRATE SYNTHASE

Citrate Synthase from porcine heart has been used:

  • to inject newt egg for determining its importance in egg activation at fertilization
  • in the preparation of reaction mix to determine pyruvate carboxylase enzyme activity
  • to examine whether it can induce a [Ca2+]?increase and egg activation in unfertilized eggs

Definition

An enzyme that catalyzes the condensation of oxaloacetic acid and acetyl-CoA to yield citric acid and coenzyme A.

Biochem/physiol Actions

Citrate synthase catalyses the conversion of citrate to acetyl-CoA in the presence of coenzyme-A with the release of H2O and oxaloacetate. The enzyme has a molecular weight of 85 kDa and a pI of 6.1-6.6. It is inhibited by fluoroacetyl-CoA, palmitoyl-CoA, and citroyl-CoA. It is also inhibited when it is acetylated by acetic anhydride or iodinated by iodine.

Properties of CITRATE SYNTHASE

storage temp.  2-8°C
solubility  H2O: soluble1.0mg/mL, clear
form  ammonium sulfate suspension

Safety information for CITRATE SYNTHASE

Computed Descriptors for CITRATE SYNTHASE

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