CITRATE SYNTHASE
Synonym(s):Citrate condensing enzyme;Citrate oxaloacetate lyase (CoA-acetylating)
- CAS NO.：9027-96-7
- Empirical Formula: C6H5O7-3
- Molecular Weight: 189.0997
- MDL number: MFCD00130808
- EINECS: 232-821-7
- Update Date: 2023-04-23 13:52:06
What is CITRATE SYNTHASE?
The Uses of CITRATE SYNTHASE
Citrate Synthase from porcine heart has been used:
- to inject newt egg for determining its importance in egg activation at fertilization
- in the preparation of reaction mix to determine pyruvate carboxylase enzyme activity
- to examine whether it can induce a [Ca2+]?increase and egg activation in unfertilized eggs
Definition
An enzyme that catalyzes the condensation of oxaloacetic acid and acetyl-CoA to yield citric acid and coenzyme A.
Biochem/physiol Actions
Citrate synthase catalyses the conversion of citrate to acetyl-CoA in the presence of coenzyme-A with the release of H2O and oxaloacetate. The enzyme has a molecular weight of 85 kDa and a pI of 6.1-6.6. It is inhibited by fluoroacetyl-CoA, palmitoyl-CoA, and citroyl-CoA. It is also inhibited when it is acetylated by acetic anhydride or iodinated by iodine.
Properties of CITRATE SYNTHASE
| storage temp. | 2-8°C |
| solubility | H2O: soluble1.0mg/mL, clear |
| form | ammonium sulfate suspension |
Safety information for CITRATE SYNTHASE
Computed Descriptors for CITRATE SYNTHASE
New Products
Tubulysin E (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin A Tubulysin H CYCLOBUTYLAMINE HYDROCHLORIDE Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 2,2-Difluoropropylamine hydrochloride tetrahydro-4-methyl-2H-pyran 2,2-Difluoropropanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH 2,3-dichloro-6- nitrobenzonitrile 4-(2-fluoro-4- nitrophenyl) thiomorpholine Magnesium Trisilicate Latanoprostene Bunod Lubiprostone Flame Retardant Zinc Borate 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
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