CIS-ACONITIC ACID

Synonym(s):cis-Propene-1,2,3-tricarboxylic acid

CAS NO.：585-84-2
Empirical Formula: C6H6O6
Molecular Weight: 174.11
MDL number: MFCD00063184
EINECS: 209-564-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is CIS-ACONITIC ACID?

Chemical properties

WHITE TO ALMOST WHITE POWDER

The Uses of CIS-ACONITIC ACID

cis-Aconitic Acid is the cis-isomer of Aconitic Acid. The conjugate base of cis-Aconitic Acid is an intermediate in the isomerization of citrate and isocitrate in the citric acid cycle.

The Uses of CIS-ACONITIC ACID

cis-Aconitic acid is used as an intermediate in the production of substances pharmaceuticals. It is widely used in chemical research and as reagent. It acts as a cis-isomer of aconitic acid.

The Uses of CIS-ACONITIC ACID

cis-Aconitic acid can be used as a standard for the determination of organic acids in plant tissues.

What are the applications of Application

cis-Aconitic acid is cis-Aconitic acid is the cis-isomer of Aconitic Acid. The conjugate base of cis-Aconitic Acid is an intermediate in the isomerization of citrate and isocitrate in the citric acid cycle.

Definition

ChEBI: The cis-isomer of aconitic acid.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Purification Methods

Crystallise the cis-acid from water by cooling (solubility is 1g in 2mL of water at 25o). Dry it in a vacuum desiccator. [Beilstein 2 IV 2405.]

Properties of CIS-ACONITIC ACID

Melting point:	122 °C (lit.)
Boiling point:	225.05°C (rough estimate)
Density	1.660
refractive index	1.5860 (estimate)
FEMA	2010 \| ACONITIC ACID
storage temp.	-20°C
solubility	Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	1.95(at 25℃)
color	White to Off-White
PH	3.05(1 mM solution);2.21(10 mM solution);1.55(100 mM solution)
Odor	bland
Water Solubility	Soluble in water, alcohol. Slightly soluble in ether.
BRN	1725829
Stability:	Hygroscopic, Light Sensitive
CAS DataBase Reference	585-84-2(CAS DataBase Reference)
EPA Substance Registry System	1-Propene-1,2,3-tricarboxylic acid, (1Z)- (585-84-2)

Safety information for CIS-ACONITIC ACID

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H350:Carcinogenicity
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention.