cis-1,2-Diaminocyclohexane

Synonym(s):cis-1,2-Cyclohexanediamine

CAS NO.：1436-59-5
Empirical Formula: C6H14N2
Molecular Weight: 114.19
MDL number: MFCD00063746
EINECS: 205-754-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-11 17:28:48

What is cis-1,2-Diaminocyclohexane?

Chemical properties

Clear colorless liquid

The Uses of cis-1,2-Diaminocyclohexane

cis-1,2-Diaminocyclohexane was used in the synthesis of platinum complexes that have high antitumor activity.It was also used in the synthesis of multidentate ligands for uranyl and transition metal complexation.

What are the applications of Application

cis-1,2-Diaminocyclohexane is a key compound for the synthesis of multidentate ligands

General Description

cis-1,2-Diaminocyclohexane perturbed the spectrum of free pyrroloquinoline quinone (PQQ), a covalently linked form of which is the carbonyl cofactor of lysyl oxidase and also induced similar changes in the spectrum of lysyl oxidase.

Purification Methods

Dry the diamine over solid KOH and distil it in a vacuum. It is a strong base, keep away from CO2, store in the dark under N2. [Beilstein 13 IV 1.]

Properties of cis-1,2-Diaminocyclohexane

Melting point:	8°C
Boiling point:	92-93 °C/18 mmHg (lit.)
Density	0.952 g/mL at 25 °C (lit.)
vapor pressure	0.4 mm Hg ( 20 °C)
refractive index	n20/D 1.493(lit.)
Flash point:	161 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Water Solubility	Completely miscible in water
form	Low Melting Solid
pka	9.93(at 20℃)
color	Brown
CAS DataBase Reference	1436-59-5(CAS DataBase Reference)
NIST Chemistry Reference	cis-1,2-Cyclohexanediamine(1436-59-5)

Safety information for cis-1,2-Diaminocyclohexane

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.