Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listCIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

  • CAS NO.:13149-00-3
  • Empirical Formula: C8H10O3
  • Molecular Weight: 154.16
  • MDL number: MFCD00005926
  • EINECS: 236-086-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-29 14:36:51
CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Structural

What is CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE?

Chemical properties

white to almost white cryst. low melting solid

The Uses of CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

(3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione is a reagent used in the synthesis of Pregabalin (P704800), a GABA analogue used as an anticonvulsant. Also used to prepare P2X7 receptor antagonists.

Purification Methods

It has been obtained by heating the trans-acid or anhydride at 200o. Crystallise it from *C6H6/Et2O or distil it. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Abell J Org Chem 22 769 1957, Beilstein 17 II 452, 17 III/IV 5931.]

Properties of CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

Melting point: 32-34 °C(lit.)
Boiling point: 158 °C17 mm Hg(lit.)
Density  1.23
refractive index  1.4750 (estimate)
Flash point: >230 °F
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Crystalline Low Melting Solid
color  White to almost white
Sensitive  Moisture Sensitive
BRN  83214
Stability: Moisture Sensitive
CAS DataBase Reference 13149-00-3(CAS DataBase Reference)

Safety information for CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Health Hazard
GHS08
GHS Hazard Statements H317:Sensitisation, Skin
H318:Serious eye damage/eye irritation
H334:Sensitisation, respiratory
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P272:Contaminated work clothing should not be allowed out of the workplace.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P284:Wear respiratory protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501:Dispose of contents/container to..…

Computed Descriptors for CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

Related products of tetrahydrofuran

You may like

  • Cis-1,2-cyclohexanedicarboxylic anhydride 98% CAS 13149-00-3
    Cis-1,2-cyclohexanedicarboxylic anhydride 98% CAS 13149-00-3
    13149-00-3
    View Details
  • cis-1,2-Cyclohexanedicarboxylic Anhydride CAS 13149-00-3
    cis-1,2-Cyclohexanedicarboxylic Anhydride CAS 13149-00-3
    13149-00-3
    View Details
  • 1975-50-4 98%
    1975-50-4 98%
    1975-50-4
    View Details
  • 2-HYDROXY BENZYL ALCOHOL 98%
    2-HYDROXY BENZYL ALCOHOL 98%
    90-01-7
    View Details
  • 2-Chloro-1,3-Bis(Dimethylamino)Trimethinium  Hexafluorophosphate 221615-75-4 98%
    2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%
    221615-75-4
    View Details
  • 61397-56-6 CIS BROMO BENZOATE 98%
    61397-56-6 CIS BROMO BENZOATE 98%
    61397-56-6
    View Details
  • 14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+
    14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+
    14714-50-2
    View Details
  • 118753-70-1 98+
    118753-70-1 98+
    118753-70-1
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.