CINCHONINE HYDROCHLORIDE
- CAS NO.：5949-11-1
- Empirical Formula: C19H23ClN2O
- Molecular Weight: 330.85
- MDL number: MFCD00079070
- EINECS: 621-239-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:14
What is CINCHONINE HYDROCHLORIDE?
Description
Cinchonine hydrochloride not only possesses the required solubility and bioavailability criteria for pharmaceutical formulations while retaining desired therapeutic properties, but is also very stable in solution, which facilitates the preparation of aqueous formulations, especially injections.
The Uses of CINCHONINE HYDROCHLORIDE
Cinchonine hydrochloride can be used as an inhibitory substance for the phenomenon of "multidrug resistance" (MDR). In particular, cinchonine hydrochloride compositions are useful in the treatment of cancer-related diseases with MDR phenomena.
Biological Activity
Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural compound in cinchona bark with antimalarial activity. It can activate endoplasmic reticulum stress to induce apoptosis in human hepatoma cells.
Properties of CINCHONINE HYDROCHLORIDE
| Melting point: | 208-218 °C(lit.) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| CAS DataBase Reference | 5949-11-1 |
Safety information for CINCHONINE HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..… |
Computed Descriptors for CINCHONINE HYDROCHLORIDE
New Products
1-Boc-4-cyanopiperidine tert-Butyl carbazate 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE TETRABUTYLAMMONIUM CYANIDE TETRAHYDRO-2H-PYRAN-3-OL 3-Pyridineacrylic acid Nickel(II) perchlorate hexahydrate, 98% 4-Bromophenylacetonitrile, 95% 3-Bromo-4-fluoroaniline, 97% Sodium tetraborate decahydrate, 98% Palladium(II) acetate, trimer, Pd 99% 4-Bromo-2-chlorotoluene, 97% Tadalafil Clopidogrel bisulfate Sitagliptin Phosphate Monohydrate Cabergoline Fexofinadine HCl Etoricoxib 4-Amino Acetophenone 2-Chloro Acetophenone Amlodipine Base 2,3,5-Triiodobenzoic Acid Pyrrolidine Diiodo PentoxideRelated products of tetrahydrofuran
You may like
-
Cinchonine hydrochloride CASView Details -
366789-02-8 Riveroxaban 98%View Details
366789-02-8 -
Phenylephrine HCl 61-76-7 98%View Details
61-76-7 -
Carvedilol 98%View Details
72956-09-3 -
Abiretorone 154229-18-2 98%View Details
154229-18-2 -
73590-58-6 Omeprazole 98%View Details
73590-58-6 -
201530-41-8 Deferasirox 98%View Details
201530-41-8 -
Sertraline HCl 98%View Details
79559-97-0