Choline Fenofibrate Impurity 1

The Uses of Choline Fenofibrate Impurity 1

4’-Chloro-2-hydroxy-benzophenone is a useful compound to investigate the effects of substituents on photo-antioxidant abilities of 2-hydroxybenzoyl compounds that can?prevent?autooxidation of plastics under UV light.4’-Chloro-2-hydroxy-benzophenone can also utilized to develop novel?Azomethine Prodrugs of (R)-α-Methylhistamine.

Preparation

Preparation by Fries rearrangement of phenyl p-chloro-benzoate,
? with aluminium chloride without solvent between 120° and 160°, (29%), at 200° for 20 min or in refluxing chlorobenzene for 10 h (53%);
? with trifluoromethanesulfonic acid at 45–55° (6%).