CHLOROMETHYL PHENYL SULFOXIDE

The Uses of CHLOROMETHYL PHENYL SULFOXIDE

Chloromethyl phenyl sulfoxide has been used in the preparation of:

• 1-chloroalkyl sulfoxides
• starting material for the synthesis alkyl sulfoxides and thiol ester acyl anion equivalent

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 4496, 1968 DOI: 10.1021/ja01018a078
Synthesis, p. 831, 1986
Tetrahedron Letters, 17, p. 613, 1976

General Description

Chloromethyl phenyl sulfoxide has synthetic potential and exhibits unusual stereochemical specificity. Stereospecific hydroxyalkylation of chloromethyl phenyl sulfoxide has been investigated.