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HomeProduct name listCGS-21680 HYDROCHLORIDE

CGS-21680 HYDROCHLORIDE

Synonym(s):2-p-(2-Carboxyethyl)phenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride hydrate;Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride - CAS 124182-57-6 - Calbiochem;CGS-21680, CGS21680, 3-(4-(2-((6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid

CGS-21680 HYDROCHLORIDE Structural

What is CGS-21680 HYDROCHLORIDE?

Chemical properties

White Solid

The Uses of CGS-21680 HYDROCHLORIDE

A selective A2A receptor agonist

Biological Activity

A 2A adenosine receptor agonist (K i = 27 nM). Has affinity for A 1 and A 3 adenosine receptors but can be used to distinguish A 2A - and A 2B -mediated effects.

Biochem/physiol Actions

Adenosine receptor agonist, which possesses selectivity for A2 verses A1 receptors.

Properties of CGS-21680 HYDROCHLORIDE

storage temp.  −20°C
solubility  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 20 mg/mL
form  solid
color  white
CAS DataBase Reference 124182-57-6

Safety information for CGS-21680 HYDROCHLORIDE

Computed Descriptors for CGS-21680 HYDROCHLORIDE

InChIKey QPHVMNOEKKJYJO-MJWSIIAUSA-N

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