CGP 42112
Synonym(s):Nα-Nicotinoyl-Tyr-(Nα-Cbz-Arg)-Lys-His-Pro-Ile
- CAS NO.:127060-75-7
- Empirical Formula: C52H69N13O11
- Molecular Weight: 1052.18
- MDL number: MFCD00133611
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is CGP 42112?
Definition
ChEBI: CGP-42112A is a hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist. It has a role as an angiotensin receptor agonist, a vasodilator agent, an antineoplastic agent, an anti-inflammatory agent and a neuroprotective agent. It is an oligopeptide, a benzyl ester and a pyridinecarboxamide.
Biochem/physiol Actions
Potent AT2 angiotensin II receptor agonist.
storage
Store at -20°C
Properties of CGP 42112
Density | 1.39±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO:350.0(Max Conc. mg/mL);332.64(Max Conc. mM) |
pka | 3.72±0.22(Predicted) |
form | solid |
color | white |
Water Solubility | Soluble to 1 mg/ml in water |
BRN | 8184948 |
Safety information for CGP 42112
Computed Descriptors for CGP 42112
New Products
SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION Azithromycin Imp D Azithromycin EP Impurity C Atracurium Besylate EP Impurity D Azithromycin EP Impurity B Azithromycin EP Impurity O Cetirizine Glycerol Ester Impurity HydrochlorideRelated products of tetrahydrofuran
(6-Aminohexyl)carbamic acid
CHEMBRDG-BB 9071485
H-PRO-ILE-OH
(2S)-1-[(2S)-2-Amino-3-(3H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxamide
CGP 42112
CHEMBRDG-BB 5402672
2-PHENYL-N-(PYRIDIN-3-YLMETHYL)ETHANAMINE
H-PRO-VAL-OH
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