CELECOXIB-D7
- CAS NO.:544686-21-7
- Empirical Formula: C17H7D7F3N3O2S
- Molecular Weight: 388.42
- MDL number: MFCD08063418
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:11
What is CELECOXIB-D7?
Description
Celecoxib-d7 is intended for use as an internal standard for the quantification of celecoxib by GC- or LC-MS. Celecoxib is a selective inhibitor of COX-2 (IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). It displays chemopreventive activity in multiple tumor types via proapoptotic effects that are independent of COX-2 inhibition. Formulations containing celecoxib have been used in the treatment of inflammation while circumventing the gastrointestinal toxicity associated with traditional non-sterodial anti-inflammatory drugs, however, the use of celecoxib has been tempered due to its ability to induce adverse cardiovascular events.
The Uses of CELECOXIB-D7
Celecoxib-d7 is the labeled analogue of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis.
Properties of CELECOXIB-D7
storage temp. | Store at -20°C |
solubility | DMSO: 76 mg/ml,Ethanol: 33 mg/ml |
form | A solid |
color | Off-white to gray |
Safety information for CELECOXIB-D7
Computed Descriptors for CELECOXIB-D7
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