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HomeProduct name listCELECOXIB-D7

CELECOXIB-D7

CELECOXIB-D7 Structural

What is CELECOXIB-D7?

Description

Celecoxib-d7 is intended for use as an internal standard for the quantification of celecoxib by GC- or LC-MS. Celecoxib is a selective inhibitor of COX-2 (IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). It displays chemopreventive activity in multiple tumor types via proapoptotic effects that are independent of COX-2 inhibition. Formulations containing celecoxib have been used in the treatment of inflammation while circumventing the gastrointestinal toxicity associated with traditional non-sterodial anti-inflammatory drugs, however, the use of celecoxib has been tempered due to its ability to induce adverse cardiovascular events.

The Uses of CELECOXIB-D7

Celecoxib-d7 is the labeled analogue of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis.

Properties of CELECOXIB-D7

storage temp.  Store at -20°C
solubility  DMSO: 76 mg/ml,Ethanol: 33 mg/ml
form  A solid
color  Off-white to gray

Safety information for CELECOXIB-D7

Computed Descriptors for CELECOXIB-D7

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