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HomeProduct name listCeftriaxone sodium

Ceftriaxone sodium

  • CAS NO.:104376-79-6
  • Empirical Formula: C18H21N8NaO8S3
  • Molecular Weight: 596.58
  • MDL number: MFCD01750405
  • EINECS: 626-956-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
Ceftriaxone sodium Structural

What is Ceftriaxone sodium?

Description

Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.

Chemical properties

White Crystalline Solid

The Uses of Ceftriaxone sodium

antipsychotic

The Uses of Ceftriaxone sodium

An antibacterial, a third-generation cephalosporin.

The Uses of Ceftriaxone sodium

A potentially useful antibacterial agent for proteomics research.

What are the applications of Application

Ceftriaxone, Disodium Salt, Hemiheptahydrate is a potentially useful antibacterial agent for proteomics research

Definition

ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin.

brand name

Rocephin (Roche).

Biological Activity

β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.

Properties of Ceftriaxone sodium

Melting point: 236 °C
alpha  D25 -165° (c = 1 in water) (calc for water-free substance)
refractive index  -160 ° (C=1, H2O)
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  H2O: soluble50mg/mL
form  powder or crystals
pka ~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH)
color  White to Off-White
Water Solubility  Freely soluble in water

Safety information for Ceftriaxone sodium

Signal word Danger
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H315:Skin corrosion/irritation
H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
H334:Sensitisation, respiratory
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Ceftriaxone sodium

InChIKey FDRNWTJTHBSPMW-BBJOQENWSA-L

Ceftriaxone sodium manufacturer

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