Ceftriaxone sodium
- CAS NO.：104376-79-6
- Empirical Formula: C18H21N8NaO8S3
- Molecular Weight: 596.58
- MDL number: MFCD01750405
- EINECS: 626-956-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is Ceftriaxone sodium?
Description
Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.
Chemical properties
White Crystalline Solid
The Uses of Ceftriaxone sodium
antipsychotic
The Uses of Ceftriaxone sodium
An antibacterial, a third-generation cephalosporin.
The Uses of Ceftriaxone sodium
A potentially useful antibacterial agent for proteomics research.
What are the applications of Application
Ceftriaxone, Disodium Salt, Hemiheptahydrate is a potentially useful antibacterial agent for proteomics research
Definition
ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin.
brand name
Rocephin (Roche).
Biological Activity
β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.
Properties of Ceftriaxone sodium
| Melting point: | 236 °C |
| alpha | D25 -165° (c = 1 in water) (calc for water-free substance) |
| refractive index | -160 ° (C=1, H2O) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | powder or crystals |
| pka | ~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH) |
| color | White to Off-White |
| Water Solubility | Freely soluble in water |
Safety information for Ceftriaxone sodium
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Ceftriaxone sodium
| InChIKey | FDRNWTJTHBSPMW-BBJOQENWSA-L |
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