CD437
Synonym(s):6-(3-(1-Adamantyl)-4-hydroxyphenyl)-2-naphthalene carboxylic acid;6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid;AHPN;Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem
- CAS NO.:125316-60-1
- Empirical Formula: C27H26O3
- Molecular Weight: 398.49
- MDL number: MFCD03106506
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:09:03
What is CD437?
Chemical properties
Yellow Solid
The Uses of CD437
An intermediate in the preparation of Adapalene derivatives.
What are the applications of Application
CD 437 is A cell-permeable retinoid-related molecule tumor growth arrest and apoptosis inducer
Definition
ChEBI: A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)g mma and induces cell cycle arrest and apoptosis in various cancer cells.
Biological Activity
Synthetic retinoid that is an RAR γ -selective agonist. Displays RAR γ -dependent and -independent effects on differentiation and apoptosis.
Biochem/physiol Actions
CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.
storage
Store at -20°C
Properties of CD437
Melting point: | 271.6-276 °C |
Boiling point: | 595.0±50.0 °C(Predicted) |
Density | 1.290 |
storage temp. | -20°C |
solubility | DMSO: 26 mg/mL |
form | solid |
pka | 4.17±0.30(Predicted) |
color | yellow |
Safety information for CD437
Computed Descriptors for CD437
Related products of tetrahydrofuran
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