C10-HOMOSERINE LACTONE
Synonym(s):N-[(3S)-Tetrahydro-2-oxo-3-furanyl]decanamide;C10-HSL
- CAS NO.:177315-87-6
- Empirical Formula: C14H25NO3
- Molecular Weight: 255.35
- MDL number: MFCD11113140
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:41
What is C10-HOMOSERINE LACTONE?
The Uses of C10-HOMOSERINE LACTONE
Decanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Burkholderia pseudomallei. Decanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.
What are the applications of Application
N-decanoyl-L-Homoserine lactone is a small signaling molecule involved in quorum sensing
Definition
ChEBI: N-decanoyl-L-Homoserine lactone is a N-acyl-amino acid.
Biochem/physiol Actions
N-Decanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.
Properties of C10-HOMOSERINE LACTONE
Melting point: | 127-130 °C |
Boiling point: | 466.1±34.0 °C(Predicted) |
Density | 1.02±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml |
form | A crystalline solid |
pka | 14.72±0.20(Predicted) |
color | White to off-white |
optical activity | [α]/D -24±3°, c = 0.2 in methanol |
Safety information for C10-HOMOSERINE LACTONE
Computed Descriptors for C10-HOMOSERINE LACTONE
New Products
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