Bromo-PEG3-Acid
- CAS NO.：782475-35-8
- Empirical Formula: C9H17BrO5
- Molecular Weight: 285.13
- MDL number: MFCD22574820
- Update Date: 2024-07-02 08:55:13
What is Bromo-PEG3-Acid?
Description
Bromo-PEG3-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
The Uses of Bromo-PEG3-Acid
This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.
Properties of Bromo-PEG3-Acid
| storage temp. | -20°C |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Bromo-PEG3-Acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Bromo-PEG3-Acid
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