Bromo-PEG1-CH2CO2H
- CAS NO.：1135131-50-8
- Empirical Formula: C4H7BrO3
- Molecular Weight: 183
- MDL number: MFCD20637665
- Update Date: 2024-10-28 23:16:16
What is Bromo-PEG1-CH2CO2H?
Description
Bromo-PEG1-CH2CO2H is a PEG linker containing a bromide group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.
Properties of Bromo-PEG1-CH2CO2H
| Boiling point: | 316.4±17.0 °C(Predicted) |
| Density | 1.683±0.06 g/cm3(Predicted) |
| pka | 3.31±0.10(Predicted) |
| form | Solid-Liquid Mixture |
| color | Colorless to off-white |
Safety information for Bromo-PEG1-CH2CO2H
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Bromo-PEG1-CH2CO2H
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