BROMETHALIN
- CAS NO.:63333-35-7
- Empirical Formula: C14H7Br3F3N3O4
- Molecular Weight: 577.93
- MDL number: MFCD01733226
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is BROMETHALIN?
Chemical properties
Pale yellow, water-insoluble crystalline substance.
The Uses of BROMETHALIN
Bromethalin is used to control rats and mice indoors and outdoors. It is more effective against rats.
The Uses of BROMETHALIN
Rodenticide.
Definition
ChEBI: Bromethalin is a C-nitro compound.
Hazard
Poisonous; moderately toxic; causes headache, confusion, personality changes, seizures, coma, death.
Metabolic pathway
Bromethalin is a complex molecule possessing several functional groups and rapid and multi-pathway metabolism would be expected. There is a dearth of information published on its environmental fate and metabolism in plants but some limited information on metabolism in rats is available.
Degradation
Bromethalin is stable under normal storage conditions but it is degraded by UV light.
Toxicity evaluation
Bromethalin is produced by reaction of 2,4-dinitro-6- trifluoromethyl methylaniline with 1,2,3,5-tetrabromobenzene (15). This compound has been known for some time to have rodenticidal properties (16) but has only recently been made available. Bromethalin is used in baits at a concentration of 0.005 or 0.01% and is effective against rodents resistant to anticoagulants. It does not induce bait shyness. Anorexia occurs after an effective dose has been consumed. The mode of action is by uncoupling oxidative phosphorylation in cells of the central nervous system. Symptoms of poisoning include tremors, convulsions, prostration, and hind-limb paralysis. No specific antidote is available but a symptomatic treatment has been described (17). Trade Names. Assault (Purina Mills), Vengeance (Dow- Elanco). The following acute and subacute compounds are used for rodent control less frequently than those listed above, either because they are not widely available or because restrictions have been placed upon their use due to safety considerations (11,18).
Properties of BROMETHALIN
Melting point: | 150.5℃ |
Boiling point: | 190°C (rough estimate) |
Density | 2.0944 (estimate) |
vapor pressure | 1.3 x l0-5 Pa (25 °C) |
solubility | Chloroform (Slightly), DMSO (Slightly) |
pka | -9.73±0.50(Predicted) |
Water Solubility | <0.1 mg l-1 |
form | Solid |
color | Light Yellow to Yellow |
EPA Substance Registry System | Bromethalin (63333-35-7) |
Safety information for BROMETHALIN
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Environment GHS09 |
GHS Hazard Statements |
H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P284:Wear respiratory protection. P310:Immediately call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for BROMETHALIN
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