BQ-788
- CAS NO.:156161-89-6
- Empirical Formula: C34H52N5NaO7
- Molecular Weight: 665.81
- MDL number: MFCD00797882
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is BQ-788?
The Uses of BQ-788
BQ-788 has been used as a selective endothelin-B (ETRB) blocker in human airway smooth muscle cells (HASMCs), uterine mesothelial cells (UtMCs)-derived vascular smooth muscle cells (VSMCs), and human umbilical vein endothelial cells (HUVECs)
What are the applications of Application
BQ 788 sodium salt is a selective Endothelin receptor B (ETBR) antagonist
Biological Activity
Potent, selective ET B receptor antagonist (IC 50 = 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells).
Biochem/physiol Actions
Selective ETB endothelin receptor antagonist.
storage
+4°C
Properties of BQ-788
storage temp. | -20°C |
solubility | acetonitrile: 0.3 mg/mL |
form | solid |
color | white |
Safety information for BQ-788
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for BQ-788
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