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HomeProduct name listBouvardin

Bouvardin

Bouvardin Structural

What is Bouvardin?

Enzyme inhibitor

This cyclic hexapeptide antitumor agent (FW = 772.86 g/mol; CAS 64755- 14-2), from Bouvardia ternifolia (scarlet bourvardia or trumpetilla), also known as NSC 259968, inhibits protein synthesis in intact eukaryotic cells and cell-free systems. Bouvardin inhibits EF1-dependent binding of aminoacyl-tRNA and EF2-dependent translocation of peptidyl-tRNA but does not affect the nonenzymic translocation since this reaction does not require EF2. Bouvardin contains L- and D-alanine, and N-methyl-L-tyrosine.

Properties of Bouvardin

Boiling point: 738.17°C (rough estimate)
Density  1.2175 (rough estimate)
refractive index  1.6400 (estimate)
pka 9.07±0.70(Predicted)

Safety information for Bouvardin

Computed Descriptors for Bouvardin

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