BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
- CAS NO.：184951-87-9
- Empirical Formula: C20H21N5O4S
- Molecular Weight: 427.48
- MDL number: MFCD01318725
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-27 16:27:43
What is BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE?
The Uses of BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
To a solution of thioanilide 7 (2 mmol) dissolved
by gentle warming at 40 °C and then cooled to 0 °C in glacial
acetic acid (diluted with 5% water, 15 mL) was added NaNO2
(0.21 g, 3 mmol) in portions over 5 min with stirring. After 30
min, ice water (～100 mL) was added, and the precipitated
product was filtered and washed with water. The orange solid
was dried in vacuo at rt overnight and then at 50 °C for 4 h to
afford benzotriazoles 1-(N-BOC-L-thionophenylalaninyl)-6-nitrobenzotriazole (9b): yield 81%. as amorphous solids of
sufficient purity for use in the next step.
Properties of BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
| Density | 1.36 |
| storage temp. | -15°C |
| pka | 10.06±0.46(Predicted) |
Safety information for BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
Computed Descriptors for BOC-THIONOPHE-1-(6-NITRO)BENZOTRIAZOLIDE
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 4-Hydrazinobenzoic acid 3,4-Dibenzyloxybenzaldehyde 3-Nitrobenzaldehyde 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) 4-HYDROXY BENZYL ALCOHOL 3-NITRO-2-METHYL ANILINE (2-Hydroxyphenyl)acetonitrile 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride tert-butyl 4- (ureidomethyl)benzylcarbamate diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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