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HomeProduct name listBoc-O-tert-butyl-L-threonine

Boc-O-tert-butyl-L-threonine

Synonym(s):(S)-3-tert-Butoxy-2-tert-butoxycarbonylamino-butyric acid;Boc-O-tert-butyl-L-threonine;Boc-Thr(tBu)-OH;N-α-t.-Boc-O-t.-butyl-L-threonine

Boc-O-tert-butyl-L-threonine Structural

What is Boc-O-tert-butyl-L-threonine?

The Uses of Boc-O-tert-butyl-L-threonine

N-Boc-O-tert-butyl-L-threonine is used as pharmaceutical intermediate.

General Description

Boc-Thr(t-Bu)-OH (N-Boc-O-tert-butyl-L-threonine) participates in the synthesis of 2,3-unsaturated glycosides, via reaction with per-O-acetylated glucal in the presence of Er(OTf)3 catalyst.

Properties of Boc-O-tert-butyl-L-threonine

Melting point: 95-98 °C
Boiling point: 391.3±37.0 °C(Predicted)
Density  1.070±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Soluble in DMF.
form  Solid
pka 3.53±0.10(Predicted)
color  White to off-white
optical activity [α]20/D +3.6±0.5°, c = 2% in DMF
BRN  4454820
CAS DataBase Reference 13734-40-2(CAS DataBase Reference)

Safety information for Boc-O-tert-butyl-L-threonine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Boc-O-tert-butyl-L-threonine

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