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HomeProduct name listBOC-Glycine

BOC-Glycine

Synonym(s):N-(tert-Butoxycarbonyl)glycine;Boc-glycine

  • CAS NO.:4530-20-5
  • Empirical Formula: C7H13NO4
  • Molecular Weight: 175.18
  • MDL number: MFCD00002690
  • EINECS: 224-864-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:30
BOC-Glycine Structural

What is BOC-Glycine?

Chemical properties

White To Off-White Powder

The Uses of BOC-Glycine

BOC-Glycine is used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents.

The Uses of BOC-Glycine

Boc-Gly-OH can be used:

  • For the esterification reaction to synthesize N-Boc amino acid esters for peptide chemistry.
  • For the synthesis of tripeptide H-Gly-Pro-Glu-OH, analogs of neuroprotective drugs.
  • As a promoter for the allylation of hydrazones and isatin.

What are the applications of Application

N-tert-Boc-glycine-OH is an anti-inflammatory agent

Synthesis Reference(s)

Tetrahedron Letters, 16, p. 4393, 1975 DOI: 10.1016/S0040-4039(00)91133-X

Properties of BOC-Glycine

Melting point: 86-89 °C(lit.)
Boiling point: 306.47°C (rough estimate)
Density  1.2843 (rough estimate)
refractive index  1.4353 (estimate)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Powder
pka 4.00±0.10(Predicted)
color  White to off-white
Water Solubility  soluble
BRN  1101514
InChI InChI=1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)
CAS DataBase Reference 4530-20-5(CAS DataBase Reference)
EPA Substance Registry System Glycine, N-[(1,1-dimethylethoxy)carbonyl]- (4530-20-5)

Safety information for BOC-Glycine

Signal word Warning
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H303:Acute toxicity,oral
H318:Serious eye damage/eye irritation
Precautionary Statement Codes P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for BOC-Glycine

InChIKey VRPJIFMKZZEXLR-UHFFFAOYSA-N
SMILES C(O)(=O)CNC(OC(C)(C)C)=O

BOC-Glycine manufacturer

JSK Chemicals

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Dr. Silviu Pharmachem Pvt., Ltd.

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product: N-tert Butoxycarbonylglycine 4530-20-5 98%
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ALS INDIA LIFE SCIENCES

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Innovative Labs

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S D Fine Chem Limited

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Anand Agencies

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ASM Organics

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