BIS(METHYLTHIO)(TRIMETHYLSILYL)METHANE

CAS NO.：37891-79-5
Empirical Formula: C6H16S2Si
Molecular Weight: 180.41
MDL number: MFCD01631301
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:36

What is BIS(METHYLTHIO)(TRIMETHYLSILYL)METHANE?

Physical properties

bp 67–70°C/10 mmHg.

The Uses of BIS(METHYLTHIO)(TRIMETHYLSILYL)METHANE

Bis(methylthio)(trimethylsilyl)methane is a reagent used for synthesis of bis(methylthio)ketene acetals from aldehydes and ketones;acyl anion synthon for conjugate additions to enones and enoates;useful for one-carbon homologations.
The bis(methylthio)ketene acetals are useful synthetic intermediates because they are readily converted into S-methyl thioesters (eq 9) or the corresponding carboxylic acids and esters. Uses of Bis(methylthio)(trimethylsilyl)methane

Preparation

prepared from lithiobis(methylthio)- methane by silylation with chlorotrimethylsilane (eq 1).Both bis(methylthio)methane and chlorotrimethylsilane are commercially available.

37891-79-5 synthesis

Properties of BIS(METHYLTHIO)(TRIMETHYLSILYL)METHANE

Boiling point:	82 °C(Press: 10.0 Torr)
Density	0.941±0.06 g/cm3(Predicted)
refractive index	1.5060-1.5100
solubility	insol H2O; sol organic solvents.
form	clear liquid
color	Colorless to Light yellow to Light orange

Safety information for BIS(METHYLTHIO)(TRIMETHYLSILYL)METHANE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…