Betulin-3-acetate
- CAS NO.：27570-20-3
- Empirical Formula: C32H52O3
- Molecular Weight: 484.75
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-21 10:59:17
What is Betulin-3-acetate?
Biological Activity
3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2 It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity.
References
1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007) 2.B?benek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018)
Properties of Betulin-3-acetate
| storage temp. | -20°C |
| solubility | DMF: 5 mg/ml |
| form | A crystalline solid |
Safety information for Betulin-3-acetate
Computed Descriptors for Betulin-3-acetate
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