BERGAPTOL

Synonym(s):4-Hydroxy7H-furo[3,2-g][1]benzopyran-7-one;4-Hydroxybergapten;5-Hydroxy-6,7-furanocoumarin;5-Hydroxypsoralen;NSC 341958

CAS NO.：486-60-2
Empirical Formula: C11H6O4
Molecular Weight: 202.16
MDL number: MFCD00210479
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-17 16:00:36

What is BERGAPTOL?

The Uses of BERGAPTOL

A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties.

Definition

ChEBI: Bergaptol is a member of psoralens and a 5-hydroxyfurocoumarin. It is a conjugate acid of a bergaptol(1-).

Properties of BERGAPTOL

Melting point:	287-290°C
Boiling point:	311.9±11.0 °C(Predicted)
Density	1.526±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	neat
pka	6.80±0.20(Predicted)
form	Solid
color	Pale Beige to Pale Brown
BRN	190104

Safety information for BERGAPTOL

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention.