Benzyl-PEG7-amino
- CAS NO.：868594-43-8
- Empirical Formula: C21H37NO7
- Molecular Weight: 415.52
- Update Date: 2024-03-25 11:48:53
What is Benzyl-PEG7-amino?
Biological Activity
Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Safety information for Benzyl-PEG7-amino
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