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HomeProduct name listBenzyl-PEG6-azide

Benzyl-PEG6-azide

Benzyl-PEG6-azide Structural

What is Benzyl-PEG6-azide?

Biological Activity

Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Safety information for Benzyl-PEG6-azide

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