BAPTA, TETRASODIUM SALT
Synonym(s):1,2- bis( o-Aminophenoxy)ethane-N,N,N?,N?-tetraacetic Acid, 4Na;1,2-bis(o-Aminophenoxy)ethane-N,N,N?,N?-tetraacetic Acid, 4Na;1,2-Bis (2-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid tetrasodium salt;BAPTA, Tetrasodium Salt;BAPTA-Na4
- CAS NO.：126824-24-6
- Empirical Formula: C22H25N2NaO10
- Molecular Weight: 500.44
- MDL number: MFCD00067691
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:11
What is BAPTA, TETRASODIUM SALT?
Chemical properties
beige powder
The Uses of BAPTA, TETRASODIUM SALT
BAPTA, Tetrasodium Salt is a selective calcium chelator with 105-fold greater affinity for Ca2+ than for Mg2+. This product is a high quality and sensitive compound for calcium signaling studies, investigation of signal transduction and apoptotic cascades, and neuroscience research.
The Uses of BAPTA, TETRASODIUM SALT
Suitable as Ca2+-indicator (fluorescence suppressed by Ca2+). Chelator with a greater selectivity for calcium compared to magnesium.
What are the applications of Application
BAPTA, Tetrasodium Salt is a high quality and sensitive compound for calcium signaling studies
General Description
Ca2+-chelator exhibiting a 105-fold greater affinity for Ca2+ (110 nM) than for Mg2+. After BAPTA complexes with Ca2+, the UV spectrum shifts from 254 to 279 nm at pH >6.0. Useful for spectrophotometric monitoring of extracellular Ca2+ levels, especially transient phenomena, because of its insensitivity to pH. Has been used for the measurement and control of Ca2+ levels in eggs, chromaffin cells, muscle cells, retinal cells, and pancreatic cells. In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg2+. Has neuroprotective effects in vitro against excitotoxic damage and spontaneous recurrent seizures, such as epilepsy.
Properties of BAPTA, TETRASODIUM SALT
| storage temp. | −20°C |
| solubility | H2O: 10 mg/mL, clear, faintly yellow |
| form | Off-white solid |
| color | White to off-white |
| Water Solubility | Soluble in water. |
| BRN | 8818619 |
Safety information for BAPTA, TETRASODIUM SALT
Computed Descriptors for BAPTA, TETRASODIUM SALT
| InChIKey | ZWSMLJACYSGFKD-UHFFFAOYSA-J |
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