Bamaluzole
- CAS NO.:87034-87-5
- Empirical Formula: C14H12ClN3O
- Molecular Weight: 273.72
- MDL number: MFCD00868674
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is Bamaluzole?
Originator
Bamaluzole,Onbio Inc.
The Uses of Bamaluzole
Bamaluzole, is a GABA receptor agonist.
Manufacturing Process
1-Chlorophenyl-2-methanol is dissolved in dimethylformamide; NaH is added and the mixture is stirred at 20°C for 1 h. After a solution of 4-chloro-1- methyl-1H-imidazo[4,5-c]pyridine [melting point 132°-134°C; obtainable by reaction of 4-methylamino-3-nitropyridine with HCl/SnCl2 to give 3-amino-2- chloro-4-methylaminopyridine (melting point 170°-173°C) and reaction with HCOOH/acetic anhydride] in dimethylformamide has been added, the mixture is stirred at 90°-95°C for 15 h. The mixture is evaporated and the residue is worked up in the customary manner to give 4-o-chlorobenzyloxy-1-methyl- 1H-imidazo[4,5-c]pyridine, melting point 132°-135°C (crystallize from ethyl acetate-tetrahydofuran).
Therapeutic Function
Anticonvulsant
Properties of Bamaluzole
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
Safety information for Bamaluzole
Computed Descriptors for Bamaluzole
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