Azithromycin dihydrate
Synonym(s):N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A;CP-62993
- CAS NO.:117772-70-0
- Empirical Formula: C38H74N2O13
- Molecular Weight: 767.01
- MDL number: MFCD01862248
- EINECS: 641-134-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-20 17:10:30
What is Azithromycin dihydrate?
Chemical properties
White Solid
The Uses of Azithromycin dihydrate
Azithromycin dihydrate has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis. It shows an azalide antimicrobial agent active in vitro against various pathogens.
The Uses of Azithromycin dihydrate
Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
The Uses of Azithromycin dihydrate
H1 antihistamine, nonsedating
What are the applications of Application
Azithromycin Dihydrate is an azalide antimicrobial agent active in vitro against various pathogens
Definition
ChEBI: Azithromycin dihydrate is a hydrate. It contains an azithromycin.
brand name
Zithromax (Pfizer); Zmax (Pfizer).
Biochem/physiol Actions
Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.
Properties of Azithromycin dihydrate
Melting point: | 126 C |
Boiling point: | 717℃ |
alpha | D26 -41.4° (c = 1 in CHCl3) |
refractive index | -47 ° (C=2, EtOH) |
RTECS | RN6960000 |
Flash point: | >110°(230°F) |
storage temp. | room temp |
solubility | Soluble in DMSO at 20mg/ml. Also soluble in chloroform or ethylene chloride |
form | powder |
color | off-white |
Sensitive | Air Sensitive |
Merck | 14,915 |
EPA Substance Registry System | 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-?-D-xylo-hexopyranosyl]oxy]-, dihydrate, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- (117772-70-0) |
Safety information for Azithromycin dihydrate
Signal word | Danger |
Pictogram(s) |
Health Hazard GHS08 |
GHS Hazard Statements |
H317:Sensitisation, Skin H334:Sensitisation, respiratory |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Azithromycin dihydrate
Abamectin manufacturer
AVD pharmaceuticals Pvt Ltd
KARPSCHEM LABORATORIES PVT. LTD.
Alembic Pharmaceuticals Limited
Calyx Chemicals and Pharmaceuticals Ltd
Mehta API Pvt. Ltd.
Infinity Laboratories Private Limited
Ebenezer Industries
Ralington Pharma
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