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HomeProduct name listAzithromycin dihydrate

Azithromycin dihydrate

Synonym(s):N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A;CP-62993

  • CAS NO.:117772-70-0
  • Empirical Formula: C38H74N2O13
  • Molecular Weight: 767.01
  • MDL number: MFCD01862248
  • EINECS: 641-134-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-20 17:10:30
Azithromycin dihydrate Structural

What is Azithromycin dihydrate?

Chemical properties

White Solid

The Uses of Azithromycin dihydrate

Azithromycin dihydrate has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis. It shows an azalide antimicrobial agent active in vitro against various pathogens.

The Uses of Azithromycin dihydrate

Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.

The Uses of Azithromycin dihydrate

H1 antihistamine, nonsedating

What are the applications of Application

Azithromycin Dihydrate is an azalide antimicrobial agent active in vitro against various pathogens

Definition

ChEBI: Azithromycin dihydrate is a hydrate. It contains an azithromycin.

brand name

Zithromax (Pfizer); Zmax (Pfizer).

Biochem/physiol Actions

Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.

Properties of Azithromycin dihydrate

Melting point: 126 C
Boiling point: 717℃
alpha  D26 -41.4° (c = 1 in CHCl3)
refractive index  -47 ° (C=2, EtOH)
RTECS  RN6960000
Flash point: >110°(230°F)
storage temp.  room temp
solubility  Soluble in DMSO at 20mg/ml. Also soluble in chloroform or ethylene chloride
form  powder
color  off-white
Sensitive  Air Sensitive
Merck  14,915
EPA Substance Registry System 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-?-D-xylo-hexopyranosyl]oxy]-, dihydrate, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- (117772-70-0)

Safety information for Azithromycin dihydrate

Signal word Danger
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H317:Sensitisation, Skin
H334:Sensitisation, respiratory
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P272:Contaminated work clothing should not be allowed out of the workplace.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P284:Wear respiratory protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.

Computed Descriptors for Azithromycin dihydrate

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