Azithromycin dihydrate

Synonym(s):N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A;CP-62993

CAS NO.：117772-70-0
Empirical Formula: C38H74N2O13
Molecular Weight: 767.01
MDL number: MFCD01862248
EINECS: 641-134-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 13:44:46

What is Azithromycin dihydrate?

Chemical properties

White Solid

The Uses of Azithromycin dihydrate

Azithromycin dihydrate has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis. It shows an azalide antimicrobial agent active in vitro against various pathogens.

The Uses of Azithromycin dihydrate

Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.

The Uses of Azithromycin dihydrate

H1 antihistamine, nonsedating

What are the applications of Application

Azithromycin Dihydrate is an azalide antimicrobial agent active in vitro against various pathogens

Definition

ChEBI: Azithromycin dihydrate is a hydrate. It contains an azithromycin.

brand name

Zithromax (Pfizer); Zmax (Pfizer).

Biochem/physiol Actions

Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.

Properties of Azithromycin dihydrate

Melting point:	126 C
Boiling point:	717℃
alpha	D26 -41.4° (c = 1 in CHCl3)
refractive index	-47 ° (C=2, EtOH)
RTECS	RN6960000
Flash point:	>110°(230°F)
storage temp.	room temp
solubility	Soluble in DMSO at 20mg/ml. Also soluble in chloroform or ethylene chloride
form	powder
color	off-white
Sensitive	Air Sensitive
Merck	14,915
EPA Substance Registry System	1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-?-D-xylo-hexopyranosyl]oxy]-, dihydrate, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- (117772-70-0)

Safety information for Azithromycin dihydrate

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H317:Sensitisation, Skin H334:Sensitisation, respiratory
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P284:Wear respiratory protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.